Complicating drug interactions further more, lumacaftor is by itself a solid inducer of CYP3A and can consequently limit the efficacy of prescription drugs which might be cleared via this metabolic pathway. Especially, the efficacy of hormonal contraceptives is impaired and different ways of contraception must be applied in order to https://rosthornin-a88765.blogmazing.com/28137303/manual-article-review-is-required-for-this-article