Mesothelioma and Work Exposure People who work with asbestos are at higher risk of mesothelioma. People who work in construction, firefighters, or military veterans are especially vulnerable. Mesothelioma primarily affects the lung lining (pleural mesothelioma) or the abdomen. In rare instances, it may affect the testicles or the heart. Consult https://vimeo.com/704931292