In an effort to rationalise the observed ABL kinase inhibitory results from a 3D structural point of view, the direct compounds I and II, as well as the freshly intended derivatives 4a, 4b, and five were docked from the catalytic kinase domains of BCR-ABLWT (PDB code: 3OXZ) and BCR-ABLT315I (PDB https://josuetmbqg.dbblog.net/4380727/the-single-best-strategy-to-use-for-indazole-ring-formation