The primary asymmetric complete synthesis of conolidine was produced by Micalizio and coworkers in 2011.[2] This synthetic route permits use of both enantiomer (mirror impression) of conolidine through an early enzymatic resolution. "We confirmed that conolidine binds to the recently recognized opioid receptor ACKR3, when showing no affinity for https://cicerof162sjy6.livebloggs.com/profile