Summary: Bone marrow (BM) metastasis remains one of the main causes of death associated with solid tumors as well as multiple myeloma (MM). Targeting the BM niche to prevent or modulate metastasis has not been successful to date. Here. we show that stromal cell-derived factor-1 (SDF-1/CXCL12) is highly expressed in active MM. https://www.opheliasmuse.com/