Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors while in the central nervous system, conolidine modulates alternate molecular targets. A Science Developments review discovered that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By https://thenewpainkillerconolidin65296.blogitright.com/39255540/a-review-of-alternative-natural-pain-relief-to-replace-traditional-painkillers